Description

1-(1-Hexynyl)-8-Iodonaphthalene is a specialized organic building block featuring a naphthalene core functionalized with an iodine atom and a terminal alkyne group. This unique molecular architecture makes it a valuable intermediate for advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex polycyclic structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring complex aromatic frameworks.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the iodine and alkyne functionalities enable modular structure-activity relationship (SAR) studies.
• Material Science: Acts as a monomer or building block for creating organic semiconductors, liquid crystals, and advanced polymers with specific electronic or optical properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Sonogashira, Suzuki-Miyaura, and Negishi couplings to form new carbon-carbon bonds.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and coordination chemistry.
• Academic & R&D: A valuable tool in university and industrial research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	1-(1-Hexynyl)-8-Iodonaphthalene
CAS No.	22360-84-5
Molecular Formula	C₁₆H₁₅I
Molecular Weight	334.20 g/mol
Synonyms	8-Iodo-1-(1-hexyn-1-yl)naphthalene; 1-Hexyn-1-yl-8-iodonaphthalene; 1-(Hex-1-yn-1-yl)-8-iodonaphthalene; Naphthalene, 1-(1-hexynyl)-8-iodo-; 8-Iodo-1-hex-1-ynylnaphthalene
EINECS	Contact for details

Quality Control

Our 1-(1-Hexynyl)-8-Iodonaphthalene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.