Description

2-[[3-(n-Ethylbutanoylamino)-2,4,6-Triiodophenyl]Oxy]Hexanoic Acid is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This high-purity intermediate is critical for ensuring the safety and efficacy of final diagnostic pharmaceutical formulations. It is essential for manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality building blocks for complex contrast agent production.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of non-ionic, iodinated X-ray contrast agents.
• Diagnostic Imaging: Enables the production of contrast media used in computed tomography (CT), angiography, and urography.
• Research & Development: Serves as a key starting material in medicinal chemistry research for developing novel diagnostic compounds.
• Fine Chemical Synthesis: Used in advanced organic synthesis for creating complex molecules with specific iodine substitution patterns.
• Contrast Agent Manufacturing: Integral to the multi-step synthesis of final drug substances like iopamidol, iohexol, and other derivatives.

Basic Information

Product Name	2-[[3-(n-Ethylbutanoylamino)-2,4,6-Triiodophenyl]Oxy]Hexanoic Acid
CAS No.	22275-42-9
Molecular Formula	C19H27I3N2O4
Molecular Weight	720.14 g/mol
Synonyms	2-[[3-(N-Ethylbutyramido)-2,4,6-triiodophenoxy]hexanoic Acid; 2-[3-(N-Ethylbutyrylamino)-2,4,6-triiodophenoxy]hexanoic Acid; 2-({3-[(Ethylamino)carbonyl]propyl}-2,4,6-triiodophenoxy)hexanoic Acid; Iopamidol Intermediate; Iohexol Related Compound; Contrast Media Intermediate A; 22275-42-9; 5-[N-(2-Hydroxyethyl)acetamido]-2,4,6-triiodoisophthalic Acid Derivative
EINECS	Contact for details

Quality Control

Our 2-[[3-(n-Ethylbutanoylamino)-2,4,6-Triiodophenyl]Oxy]Hexanoic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are available upon request. Production can be aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.