Description

3-(Trifluoromethyl)Benzoic Acid Hydrazide is a specialized aromatic hydrazide derivative characterized by a reactive hydrazide group and a trifluoromethyl substituent. This unique structure makes it a valuable high-purity building block for synthesizing more complex heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D, agrochemical manufacturers, and advanced material scientists for creating novel molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of heterocyclic compounds like pyrazoles, triazoles, and oxadiazoles with potential biological activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the CF3 group often improves metabolic stability and lipophilicity.
• Ligand and Chelating Agent: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation studies.
• Polymer Modification: Employed to introduce hydrazide functionality into polymer chains for cross-linking or to impart specific chemical reactivity.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new chemical entities in medicinal and material chemistry.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of complex organic dyes and pigments.

Basic Information

Product Name	3-(Trifluoromethyl)Benzoic Acid Hydrazide
CAS No.	22227-25-4
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	3-(Trifluoromethyl)benzohydrazide; m-(Trifluoromethyl)benzoic acid hydrazide; α,α,α-Trifluoro-m-toluic acid hydrazide; Benzoic acid, 3-(trifluoromethyl)-, hydrazide; 3-Trifluoromethylbenzohydrazide; m-Trifluoromethylbenzoylhydrazine; 3-Carboxy-α,α,α-trifluorotoluene hydrazide
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Benzoic Acid Hydrazide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.