Description

α-Ketoglutaric Acid Monosodium Salt is a key biochemical intermediate, the monosodium salt form of α-ketoglutarate. This compound is essential in cellular metabolism, serving as a critical substrate in the Krebs cycle and as a nitrogen scavenger in amino acid biosynthesis. It is primarily utilized in the pharmaceutical, nutraceutical, and research sectors for applications ranging from cell culture media supplementation to the development of therapeutic and nutritional products.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and as a component in parenteral nutrition solutions.
• Cell Culture & Fermentation: Serves as a vital metabolic substrate in mammalian cell culture media and microbial fermentation processes to enhance cell growth and product yield.
• Nutraceuticals & Dietary Supplements: Incorporated into formulations targeting athletic performance, muscle recovery, and anti-aging due to its role in energy metabolism and protein synthesis.
• Biochemical Research: Employed as a standard, reagent, or key metabolite in enzymatic studies, metabolic pathway analysis, and mitochondrial function research.
• Diagnostic Reagents: Used in the formulation of in-vitro diagnostic kits for clinical chemistry assays.
• Cosmeceuticals: Found in advanced skincare products for its potential role in promoting collagen synthesis and cellular energy.

Basic Information

Product Name	α-Ketoglutaric Acid Monosodium Salt
CAS No.	22202-68-2
Molecular Formula	C5H7NaO5
Molecular Weight	170.10 g/mol
Synonyms	2-Oxoglutaric Acid Monosodium Salt; Sodium 2-Oxopentanedioate; Monosodium α-Ketoglutarate; AKG Na Salt; Oxoglutaric Acid Sodium Salt; 2-Oxopentanedioic Acid Monosodium Salt; Sodium α-Ketoglutarate
EINECS	244-823-0

Quality Control

Our α-Ketoglutaric Acid Monosodium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (5% solution)	6.0 - 8.0
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.