Description

3-Acetamido-2,4,6-Triiodo-Benzoate is a high-purity, iodine-rich organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This compound matters for its critical role in producing diagnostic imaging agents that require high radiopacity and specific pharmacokinetic profiles. Pharmaceutical manufacturers and advanced chemical synthesis facilities need this material to develop and produce non-ionic, low-osmolar contrast agents for enhanced patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of iodinated X-ray contrast agents such as iopamidol, iohexol, and ioversol.
• Diagnostic Imaging: Serves as a precursor for non-ionic, low-osmolar contrast media used in computed tomography (CT), angiography, and urography.
• Chemical Research: Used in academic and industrial R&D for developing novel iodinated aromatic compounds with potential medical applications.
• Radiopharmaceuticals: Potential intermediate in the research and development of targeted imaging agents.
• Specialty Chemical Synthesis: Employed in organic synthesis to introduce a highly functionalized, tri-iodinated benzene core into complex molecules.

Basic Information

Product Name	3-Acetamido-2,4,6-Triiodo-Benzoate
CAS No.	22154-43-4
Molecular Formula	C9H6I3NO3
Molecular Weight	620.86 g/mol
Synonyms	Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-; 3-Acetamido-2,4,6-triiodobenzoic acid; 2,4,6-Triiodo-3-acetamidobenzoic acid; 3-Acetylamino-2,4,6-triiodobenzoic acid; Acetrizoat; Triiodo-3-acetamidobenzoate; Iodinated benzoic acid derivative; Contrast media intermediate
EINECS	Contact for details

Quality Control

Our 3-Acetamido-2,4,6-Triiodo-Benzoate is manufactured under strict quality management systems. We provide material suitable for pharmaceutical intermediate applications, with quality controls aligned with ICH guidelines. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.