Description

2-Cyanobenzyl Bromide is a versatile and highly reactive aromatic building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in the dual functionality of the benzyl bromide and nitrile groups, enabling efficient alkylation and subsequent functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for constructing complex molecules and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its structure contributes to the final compound's biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in novel synthetic route exploration.

Basic Information

Product Name	2-Cyanobenzyl Bromide
CAS No.	22115-41-9
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	2-(Bromomethyl)benzonitrile; α-Bromo-o-tolunitrile; o-Cyanobenzyl Bromide; (2-Cyanophenyl)methyl Bromide; 2-Bromomethylbenzonitrile; Bromomethylbenzonitrile; 1-Bromo-2-(cyanomethyl)benzene; 2-(Bromomethyl)phenyl cyanide
EINECS	244-778-9

Quality Control

Our 2-Cyanobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.