Description

3-(3-Methoxyphenyl)-1,1,1-Trifluoro-2-Propanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the trifluoroacetyl group, which serves as a versatile precursor for introducing the pharmacologically important trifluoromethyl moiety into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting metabolic and central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of trifluoromethyl-substituted bioactive molecules, including potential drug candidates for CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for synthesizing fluorinated organic compounds with potential applications in advanced polymers, liquid crystals, or organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and ligands for studying enzyme mechanisms and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(3-Methoxyphenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	22102-09-6
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-(3-Methoxyphenyl)-3,3,3-trifluoro-1-propanone; 3,3,3-Trifluoro-1-(3-methoxyphenyl)-1-propanone; 3-Methoxy-ω,ω,ω-trifluoroacetophenone; 3'-Methoxy-3,3,3-trifluoropropiophenone; m-Methoxy-α,α,α-trifluoroacetophenone; 3-Methoxyphenyl Trifluoromethyl Ketone; 22102-09-6; 3-(3-Methoxyphenyl)-1,1,1-trifluoropropan-2-one
EINECS	Contact for details

Quality Control

Our 3-(3-Methoxyphenyl)-1,1,1-Trifluoro-2-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.