Description

4,4,4-Trifluoro-2-(4-Methoxy-Phenyl)-3-Oxo-Butyronitrile is a high-value fluorinated organic intermediate featuring a trifluoromethyl ketone and a nitrile group. This compound is critical for its role as a versatile building block in advanced synthetic chemistry, enabling the introduction of fluorine atoms and specific functional groups into target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials with unique optical or electronic properties.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fluorine Chemistry Research: An essential compound for academic and industrial research focused on methodologies for incorporating fluorine into complex organic architectures.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	4,4,4-Trifluoro-2-(4-Methoxy-Phenyl)-3-Oxo-Butyronitrile
CAS No.	22102-05-2
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	4,4,4-Trifluoro-3-oxo-2-(4-methoxyphenyl)butanenitrile; 2-(4-Methoxyphenyl)-4,4,4-trifluoro-3-oxobutanenitrile; 4-Methoxyphenyl trifluoromethyl ketone cyanomethyl; α-Cyano-4-methoxybenzyl trifluoromethyl ketone; 4,4,4-Trifluoro-2-(4-methoxyphenyl)-3-oxobutyronitrile; (4-Methoxyphenyl)(trifluoroacetyl)acetonitrile; TFMOB; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-2-(4-Methoxy-Phenyl)-3-Oxo-Butyronitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.