Description

Disopyramid Phosphate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is critical for the synthesis of antiarrhythmic medications, where consistent quality and purity are paramount for efficacy and safety. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical API Synthesis: As a key intermediate in the production of Class IA antiarrhythmic drugs.
• Cardiovascular Drug Manufacturing: For the formulation of medications used to treat ventricular and supraventricular arrhythmias.
• Biomedical Research: As a reference standard or active compound in pharmacological and pharmacokinetic studies.
• Fine Chemical Production: Serves as a building block for more complex pharmaceutical molecules in advanced synthesis.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations specializing in the production of generic or novel drug formulations.
• Regulatory & Quality Control: Used as an analytical standard for method development, validation, and quality assurance testing.

Basic Information

Product Name	Disopyramid Phosphate
CAS No.	22059-60-5
Molecular Formula	C21H29N3O.H3PO4
Molecular Weight	437.46 g/mol
Synonyms	Disopyramide Phosphate; α-[2-[Bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide phosphate; SC-7031; Rythmodan; Norpace; 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide phosphate; Disopyramide Phosphate Salt
EINECS	244-754-1

Quality Control

Our Disopyramid Phosphate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligning with common pharmacopeial requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.