Description

3-Cyclobutylacrylonitrile is a versatile nitrile building block featuring a cyclobutyl group and an acrylonitrile moiety. This compound is valued for its role as a key synthetic intermediate in the preparation of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists for constructing novel chemical entities. The product is supplied to meet the stringent quality requirements of advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a cyclobutane scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the nitrile functionality is a key reactive handle.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Organic Synthesis Reagent: Employed in various name reactions, including Michael additions and cycloadditions, to introduce the cyclobutylacrylonitrile unit into target molecules.
• Ligand and Catalyst Development: Utilized as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Integral in the multi-step synthesis of complex fine chemicals and flavors & fragrances.

Basic Information

Product Name	3-Cyclobutylacrylonitrile
CAS No.	22046-85-1
Molecular Formula	C7H9N
Molecular Weight	107.15 g/mol
Synonyms	3-Cyclobutyl-2-propenenitrile; (E)-3-Cyclobutylacrylonitrile; 2-Propenenitrile, 3-cyclobutyl-; Cyclobutylacrylonitrile; 3-Cyclobutylprop-2-enenitrile; trans-3-Cyclobutylacrylonitrile; NSC 163046
EINECS	Contact for details

Quality Control

Our 3-Cyclobutylacrylonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.