Description

Tris(2,2,3,3-Tetrafluoropropyl)Orthoformate is a specialized fluorinated orthoformate derivative, serving as a key reagent in advanced organic synthesis. Its primary value lies in its ability to act as a protected formyl anion equivalent and a versatile building block for introducing fluorinated moieties, which are critical for modifying the physical and chemical properties of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where the incorporation of fluorine atoms is a strategic approach to enhance metabolic stability, bioavailability, and material performance.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs to improve lipophilicity and metabolic stability.
• Agrochemical Synthesis: Serves as a key precursor for creating novel fluorinated pesticides and herbicides with enhanced efficacy and environmental profile.
• Fluorinated Material Production: Employed in the development of specialty polymers, liquid crystals, and coatings where fluorine content imparts unique properties like chemical resistance and low surface energy.
• Organic Synthesis Reagent: Functions as a versatile reagent for formylation reactions and as a protecting group in complex multi-step syntheses, particularly under anhydrous conditions.
• Electrolyte Additive Research: Investigated for use in lithium-ion battery electrolytes to improve stability and performance at high voltages.

Basic Information

Product Name	Tris(2,2,3,3-Tetrafluoropropyl)Orthoformate
CAS No.	21983-88-0
Molecular Formula	C10H7F12O3
Molecular Weight	412.14 g/mol
Synonyms	Orthoformic Acid Tris(2,2,3,3-Tetrafluoropropyl) Ester; Tris(1H,1H,5H-Octafluoropentyl) Orthoformate; 1,1,1-Tris(2,2,3,3-Tetrafluoropropoxy)Methane; HC(OCH2CF2CF2H)3; Tris(2,2,3,3-Tetrafluoropropyl) Orthoformate; Tris(Perfluoropropyl) Orthoformate (common name); Tris(2,2,3,3-Tetrafluoropropoxy)Methane
EINECS	Contact for details

Quality Control

Our Tris(2,2,3,3-Tetrafluoropropyl)Orthoformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition upon exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.