Description

2,2,3,3,3-Pentafluoro-n-(1-Naphthalenyl)Propanamide is a specialized fluorinated organic compound that serves as a high-value synthetic intermediate. Its unique structure, featuring a pentafluoroethyl group linked to a naphthalene ring system, makes it a critical building block for advanced materials and fine chemical synthesis. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides where the fluorine atoms contribute to enhanced activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic materials, contributing to the dielectric anisotropy and stability of display components.
• Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, such as oil and water repellency (oleophobicity/hydrophobicity).
• Organic Synthesis Reagent: Employed in cross-coupling reactions and amide bond formation to introduce the bulky, electron-withdrawing pentafluoroethyl-naphthyl moiety.
• Fluorinated Surfactant & Coating Research: Investigated for creating high-performance surfactants and surface coatings with low surface energy.

Basic Information

Product Name	2,2,3,3,3-Pentafluoro-n-(1-Naphthalenyl)Propanamide
CAS No.	21970-67-2
Molecular Formula	C₁₃H₈F₅NO
Molecular Weight	289.20 g/mol
Synonyms	N-(1-Naphthyl)-2,2,3,3,3-pentafluoropropanamide; 2,2,3,3,3-Pentafluoro-N-1-naphthylpropanamide; 1-Naphthalenamine, N-(2,2,3,3,3-pentafluoro-1-oxopropyl)-; Pentafluoro-N-(1-naphthyl)propionamide; N-1-Naphthylpentafluoropropionamide; α,α,β,β,β-Pentafluoro-N-1-naphthylpropionamide
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Each batch of 2,2,3,3,3-Pentafluoro-n-(1-Naphthalenyl)Propanamide is analyzed to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters are provided with every shipment. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.