Description

Boc-Cys(Dpm)-Oh CAS NO 21947-97-7 is a protected cysteine derivative, a crucial building block in the synthesis of complex peptides and bioconjugates. Its value lies in the orthogonal protection strategy it offers, where the Boc (tert-butoxycarbonyl) group safeguards the amino function and the Dpm (diphenylmethyl) group protects the thiol side chain, enabling precise sequential deprotection during solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for developing therapeutic peptides, diagnostic probes, and novel biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of cysteine residues into peptide chains, allowing for the formation of disulfide bridges critical for protein folding and stability.
• Pharmaceutical Research: Used in the development of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Serves as a precursor for site-specific labeling of proteins, antibodies, and other biomolecules with fluorophores, drugs, or other functional groups via the thiol moiety.
• Chemical Biology Probes: Enables the synthesis of probes for studying protein-protein interactions, enzyme activity, and cellular pathways.
• Material Science: Used in creating peptide-derived polymers and surfaces with specific biofunctional properties.

Basic Information

Product Name	Boc-Cys(Dpm)-Oh
CAS No.	21947-97-7
Molecular Formula	C₂₁H₂₅NO₄S
Molecular Weight	387.49 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-S-(diphenylmethyl)-L-cysteine; Boc-Cys(Dpm)-OH; Boc-S-(diphenylmethyl)-L-cysteine; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[diphenylmethylsulfanyl]propanoic acid; N-Boc-S-Dpm-L-cysteine; Boc-L-Cys(Dpm)-OH; tert-Butyloxycarbonyl-S-diphenylmethyl-L-cysteine; L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(diphenylmethyl)-
EINECS	Contact for details

Quality Control

Our Boc-Cys(Dpm)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.