Description

N(6)-(Methylnitroso)Adenosine is a specialized nucleoside derivative of significant interest in biochemical and pharmacological research. This compound serves as a critical reference standard and a key intermediate in the study of nucleic acid alkylation and mutagenesis processes. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in toxicology studies, carcinogenesis research, and the development of analytical methods. The product is supplied with a focus on high purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Biochemical Research: Used as a reference standard in studies of DNA/RNA adduct formation and nitroso compound reactivity.
• Toxicology & Carcinogenesis: Serves as a model compound for investigating the mechanisms of nitrosamine-induced mutagenesis and carcinogenicity.
• Analytical Chemistry: Employed as a high-purity calibrant or internal standard in LC-MS, HPLC, and other chromatographic methods for quantifying nucleic acid modifications.
• Pharmaceutical Development: Acts as a key intermediate or impurity standard in the synthesis and quality control of nucleoside-based therapeutics.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and organic chemistry of nucleosides.

Basic Information

Product Name	N(6)-(Methylnitroso)Adenosine
CAS No.	21928-82-5
Molecular Formula	C11H14N6O5
Molecular Weight	310.27 g/mol
Synonyms	6-(Methylnitrosoamino)purine riboside; N6-(Methylnitroso)-9-β-D-ribofuranosyladenine; N6-Methyl-N6-nitrosoadenosine; Adenosine, N6-(methylnitroso)-; 6-(N-Methyl-N-nitroso)aminopurine riboside; MNNA; N6-MNO-Adenosine
EINECS	Contact for details

Quality Control

Our N(6)-(Methylnitroso)Adenosine is manufactured under controlled conditions to ensure the highest standards of purity and identity. Each batch is subjected to rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.