Description

3-(Trimethylammonium)Propanesulfonate, Inner Salt is a high-purity zwitterionic compound, widely recognized as a key buffer component and stabilizer in biochemical and analytical applications. Its unique structure provides excellent solubility and compatibility in aqueous systems, making it indispensable for maintaining pH stability and ionic strength. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors, where precise buffer conditions are critical for protein stability, enzyme activity, and chromatographic separations.

Application

• Biochemical Buffer: A key component in zwitterionic buffers (e.g., CHAPS-like systems) for protein purification, electrophoresis, and cell culture media.
• Pharmaceutical Formulations: Used as a stabilizer and excipient in injectable and ophthalmic solutions to enhance product shelf-life.
• Diagnostic Reagents: Employed in the formulation of assay buffers and calibration standards for clinical diagnostics and research kits.
• Chromatography: Serves as a mobile phase additive in HPLC and capillary electrophoresis to improve peak shape and separation efficiency for biomolecules.
• Molecular Biology: Utilized in nucleic acid extraction and purification protocols, as well as PCR buffer systems.
• Cosmetic & Personal Care: Acts as a mild surfactant and viscosity modifier in high-end skincare formulations.

Basic Information

Product Name	3-(Trimethylammonium)Propanesulfonate, Inner Salt
CAS No.	21865-17-8
Molecular Formula	C6H15NO3S
Molecular Weight	181.25 g/mol
Synonyms	3-(Trimethylammonio)propanesulfonate; (3-Sulfopropyl)trimethylammonium inner salt; Trimethyl(3-sulfopropyl)ammonium hydroxide inner salt; TPS; TMAPS; Zwittergent 3-12; Sulfobetaine; 21865-17-8; 3-(N,N,N-Trimethylammonium)propanesulfonate
EINECS	244-622-1

Quality Control

Our 3-(Trimethylammonium)Propanesulfonate, Inner Salt is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive biochemical and pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We support compliance with cGMP, ISO 9001, and REACH frameworks to guarantee supply chain reliability and product consistency for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect purity and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
pH (1% Solution)	6.0 - 8.0
Solubility (in Water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.