Description

3-(2-Oxo-1-Pyrrolidinyl)-2,4,6-Triiodophenylacetic Acid Sodium Salt is a key iodinated organic compound, primarily valued as a critical intermediate in the synthesis of advanced X-ray contrast media. This high-purity building block is essential for ensuring the safety and efficacy of final diagnostic formulations. It is specifically engineered for use by pharmaceutical manufacturers and fine chemical synthesis facilities engaged in the production of non-ionic, low-osmolar contrast agents.

Application

• Primary Intermediate for X-ray Contrast Media: A crucial building block in the synthesis of iopromide, ioversol, and other non-ionic contrast agents.
• Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step organic synthesis to create the core triiodinated benzene structure essential for radiographic imaging.
• Research & Development (R&D): Serves as a reference standard and starting material for developing new iodinated diagnostic compounds in academic and industrial labs.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of specialized diagnostic agents.
• Quality Control & Analytical Standards: Used to prepare analytical standards for HPLC and other methods to ensure batch-to-batch consistency of final contrast media products.

Basic Information

Product Name	3-(2-Oxo-1-Pyrrolidinyl)-2,4,6-Triiodophenylacetic Acid Sodium Salt
CAS No.	21762-02-7
Molecular Formula	C14H12I3NNaO4
Molecular Weight	695.95 g/mol
Synonyms	5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid Sodium Salt; Iopromide Intermediate; Sodium 3-(2-Oxo-1-pyrrolidinyl)-2,4,6-triiodophenylacetate; 2,4,6-Triiodo-3-(1-oxo-2-pyrrolidinyl)phenylacetic Acid Sodium Salt; Ioversol Related Compound; Iopromide Sodium Salt; Iodinated Phenylacetic Acid Derivative; NX-273 Intermediate
EINECS	Contact for details

Quality Control

Our 3-(2-Oxo-1-Pyrrolidinyl)-2,4,6-Triiodophenylacetic Acid Sodium Salt is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.