Description

2-[(4-Methylphenyl)Thio]Acetonitrile is a versatile sulfur-containing nitrile building block, primarily valued for its role as a key intermediate in the synthesis of more complex heterocyclic and pharmaceutical compounds. Its molecular structure, featuring a thioether-linked aromatic ring and a reactive nitrile group, makes it a crucial precursor for constructing molecules with specific biological activities. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its sulfur and nitrile functionalities.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing thioether-linked heterocycles, such as thiazoles and benzothiazoles, which are common scaffolds in medicinal chemistry.
• Material Science Research: Investigated as a monomer or additive in the development of specialty polymers and advanced materials with unique electronic or optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways involving sulfur-nitrogen chemistry.

Basic Information

Product Name	2-[(4-Methylphenyl)Thio]Acetonitrile
CAS No.	21681-88-9
Molecular Formula	C9H9NS
Molecular Weight	163.24 g/mol
Synonyms	(4-Methylphenylthio)acetonitrile; p-Tolylthiocyanomethane; 2-(p-Tolylthio)acetonitrile; 2-(4-Methylphenylsulfanyl)acetonitrile; 2-(4-Methylphenylthio)ethanenitrile; 4-Methylbenzenethioacetonitrile; α-[(4-Methylphenyl)thio]acetonitrile; p-Methylphenyl thiocyanomethyl ether (archaic)
EINECS	Contact for details

Quality Control

Our 2-[(4-Methylphenyl)Thio]Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark cabinet.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.