Description

3-Chlorobenzoylacetonitrile is a versatile and high-purity organic building block, specifically a substituted acetonitrile derivative, essential for advanced chemical synthesis. Its reactive nitrile and carbonyl groups make it a critical intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including pyrazoles, pyrimidines, and isoxazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic ring for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers due to its electron-withdrawing properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring specific chlorinated aromatic backbones.

Basic Information

Product Name	3-Chlorobenzoylacetonitrile
CAS No.	21667-62-9
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	3'-Chlorobenzoylacetonitrile; 1-(3-Chlorophenyl)-3-oxopropanenitrile; 3-Chloro-ω-cyanacetophenone; (3-Chlorobenzoyl)acetonitrile; 3-Chlorobenzoylmethyl cyanide; 2-Oxo-2-(3-chlorophenyl)acetonitrile; 3-Chlorophenacyl cyanide; m-Chlorobenzoylacetonitrile
EINECS	244-524-6

Quality Control

Our 3-Chlorobenzoylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.