Description

3-Fluorobenzoylacetonitrile is a versatile fluorinated organic intermediate characterized by its reactive nitrile and carbonyl functional groups. This compound is crucial for the synthesis of complex heterocyclic and pharmaceutical molecules, offering a strategic entry point for introducing fluorine atoms to enhance metabolic stability and binding affinity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of novel herbicides and pesticides where the fluorine atom improves biological activity and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for β-ketonitrile ligands used in coordination chemistry and catalytic processes.
• Heterocyclic Chemistry: Fundamental starting material for constructing pyrazole, isoxazole, and pyrimidine rings in medicinal and materials chemistry.
• Advanced Material Research: Employed in the development of organic semiconductors and liquid crystals due to its molecular structure and electronic properties.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and reaction pathways in academic and industrial labs.

Basic Information

Product Name	3-Fluorobenzoylacetonitrile
CAS No.	21667-61-8
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	3-Fluorobenzoylacetonitrile; 1-(3-Fluorophenyl)-1,3-butanedione nitrile; 3-Fluorobenzoyl methyl cyanide; 4-Oxo-4-(3-fluorophenyl)butanenitrile; 3-Fluorobenzoylacetonitrile; (3-Fluorobenzoyl)acetonitrile; m-Fluorobenzoylacetonitrile; 3-Fluorobenzoic acid cyanomethyl ketone
EINECS	Contact for details

Quality Control

Our 3-Fluorobenzoylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.