Description

Cefapirin CAS NO 21593-23-7 is a first-generation cephalosporin antibiotic belonging to the β-lactam class, valued for its bactericidal activity against a range of Gram-positive and some Gram-negative organisms. Its primary commercial importance lies in its use as a key active pharmaceutical ingredient (API) and intermediate in the synthesis of sterile injectable formulations. This product is essential for manufacturers in the pharmaceutical industry, particularly those producing veterinary and human parenteral antibiotics, as well as for research institutions developing new antimicrobial agents.

Application

• Active Pharmaceutical Ingredient (API) for injectable antibiotic formulations.
• Manufacturing of sterile powders for reconstitution in hospital and clinical settings.
• Key intermediate in the synthesis of advanced cephalosporin derivatives.
• Veterinary pharmaceutical applications for treating bacterial infections in livestock.
• Reference standard for quality control and analytical testing in pharmaceutical labs.
• Research and development of novel antibiotic combinations and delivery systems.

Basic Information

Product Name	Cefapirin
CAS No.	21593-23-7
Molecular Formula	C17H17N3O6S2
Molecular Weight	423.46 g/mol
Synonyms	Cephapirin; Cefapirin Sodium; Cefaloject; Cefatrex; BL-P 1322; 3-[(Acetyloxy)methyl]-8-oxo-7-[[(4-pyridinylthio)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[2-(4-pyridylthio)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EINECS	244-449-6

Quality Control

Our Cefapirin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, potency, and purity. We support compliance with cGMP, ICH Q7, and relevant pharmacopeial guidelines (USP/EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Microbial Limits	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.