Description

2,3-Dihydro-1-[3-(Trifluoromethyl)Phenyl]-1H-Indazol-3-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazolone core and trifluoromethylphenyl substituent. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its specific structural motif.
• Material Science: Potential building block for specialty polymers and advanced organic electronic materials requiring specific fluorinated aromatic components.

Basic Information

Product Name	2,3-Dihydro-1-[3-(Trifluoromethyl)Phenyl]-1H-Indazol-3-One
CAS No.	21486-29-3
Molecular Formula	C14H9F3N2O
Molecular Weight	278.23 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-1H-indazol-3(2H)-one; 1-(3-Trifluoromethylphenyl)-2,3-dihydro-1H-indazol-3-one; 3(2H)-Indazolone, 1-[3-(trifluoromethyl)phenyl]-2,3-dihydro-; 1-(α,α,α-Trifluoro-m-tolyl)-2,3-dihydro-1H-indazol-3-one; 21486-29-3; 1-(3-Trifluoromethylphenyl)-1H-indazol-3-ol; 3-Hydroxy-1-(3-trifluoromethylphenyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-[3-(Trifluoromethyl)Phenyl]-1H-Indazol-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.