Description

H-His-Ser-Oh is a synthetic tripeptide derivative of the sequence Histidine-Serine. This compound is a valuable building block in peptide synthesis and biochemical research, offering a specific sequence for studying protein-protein interactions and enzyme mechanisms. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in peptide-based drug discovery and proteomics.

Application

• Peptide Synthesis Building Block: Used as a key intermediate in the solid-phase or solution-phase synthesis of longer, biologically active peptides.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate kinase and phosphatase activity related to the Ser-His sequence motif.
• Pharmaceutical Development: Employed in the research and development of novel therapeutic peptides targeting specific metabolic or signaling pathways.
• Proteomics & Mass Spectrometry: Acts as a reference standard or calibrant in analytical workflows for peptide identification and quantification.
• Chemical Biology Probes: Utilized to create labeled probes for studying histidine and serine's role in metal binding and catalytic sites.

Basic Information

Product Name	H-His-Ser-Oh
CAS No.	21438-60-8
Molecular Formula	C12H17N5O4
Molecular Weight	295.30 g/mol
Synonyms	Histidylserine; L-Histidyl-L-serine; H-His-Ser-OH; His-Ser; Histidine Serine Dipeptide; 2-[(2-Amino-3-(1H-imidazol-4-yl)propanoyl)amino]-3-hydroxypropanoic acid; L-Histidine-L-serine; Ser-His
EINECS	Contact for details

Quality Control

Our H-His-Ser-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistent quality and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 5.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.