Description

2-Chloro-4-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a chloro and a methyl substituent on the benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl-nitrile or halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chloro and nitrile groups serve as reactive handles for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A valuable building block for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Chloro-4-Methylbenzonitrile
CAS No.	21423-84-7
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	2-Chloro-p-tolunitrile; 4-Methyl-2-chlorobenzonitrile; 2-Chloro-4-methylbenzenecarbonitrile; Benzonitrile, 2-chloro-4-methyl-; 2-Chloro-4-cyanotoluene; 2-Chloro-4-tolunitrile; 2-Chloro-4-methyl-benzonitril
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methylbenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.