Description

3-Chloro-4-Methylbenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and methyl substituents, provides unique reactivity and steric properties essential for constructing complex molecules. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its halogenated aromatic structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	3-Chloro-4-Methylbenzonitrile
CAS No.	21423-81-4
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	4-Methyl-3-chlorobenzonitrile; 3-Chloro-p-tolunitrile; 3-Chloro-4-methylbenzenecarbonitrile; 2-Chloro-4-cyanotoluene; Benzonitrile, 3-chloro-4-methyl-; 3-Chloro-4-methyl-benzonitril; 3-Chloro-4-methylphenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Methylbenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.