Description

(5R)-5-Methyl-2-pyrrolidinone is a high-purity, chiral lactam derivative of significant industrial and research interest. Its value lies in its role as a versatile chiral building block and polar aprotic solvent, enabling precise stereochemical control in complex syntheses. This compound is essential for pharmaceutical R&D, agrochemical manufacturing, and advanced material science where optical purity is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Specialty Solvent: Functions as a high-boiling, polar aprotic solvent for demanding organic reactions, including polymerizations and condensations.
• Ligand & Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Electronic Chemicals: Employed in the formulation of advanced photoresists and cleaning agents for the electronics industry.
• Research & Development: A valuable standard and reagent in academic and industrial laboratories for method development and chiral studies.

Basic Information

Product Name	(5R)-5-Methyl-2-pyrrolidinone
CAS No.	21395-93-7
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	(R)-5-Methyl-2-pyrrolidinone; (R)-5-Methylpyrrolidin-2-one; (R)-5-Methyl-2-pyrrolidone; D-(-)-5-Methyl-2-pyrrolidinone; (5R)-5-Methylpyrrolidin-2-one; (R)-5-Methyl-2-oxopyrrolidine; (R)-5-Methyl-dihydro-2(3H)-furanone (tautomer); LMP (abbreviation in some contexts)
EINECS	Contact for details

Quality Control

Our (5R)-5-Methyl-2-pyrrolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing specific chromatographic and spectroscopic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (R-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.