Description

n-Hexyllithium is a highly reactive organolithium compound widely used as a powerful nucleophile and strong base in organic synthesis. Its value lies in its ability to efficiently introduce the n-hexyl group into a variety of substrates, enabling the construction of complex carbon frameworks. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, particularly for fine chemical synthesis and polymer initiation.

Application

• Pharmaceutical Intermediate Synthesis: As a key reagent for carbon-carbon bond formation in the production of active pharmaceutical ingredients (APIs).
• Polymer & Elastomer Initiation: Serving as an anionic initiator for the polymerization of dienes and styrenes to produce specialized synthetic rubbers and block copolymers.
• Agrochemical Manufacturing: Used in the synthesis of complex molecules for crop protection agents and herbicides.
• Fine Chemical Production: Employed in the preparation of specialty chemicals, ligands, and advanced organic compounds.
• Material Science Research: Facilitating the development of novel organic electronic materials and liquid crystals.
• Lithiation Reactions: For directed ortho-metalation (DoM) and other regioselective deprotonation strategies in complex molecule synthesis.

Basic Information

Product Name	n-Hexyllithium
CAS No.	21369-64-2
Molecular Formula	C6H13Li
Molecular Weight	92.11 g/mol
Synonyms	Hexyllithium; 1-Hexyllithium; Lithium hexyl; n-C6H13Li; Lithium n-hexyl; Hexan-1-yllithium
EINECS	Contact for details

Quality Control

Our n-Hexyllithium is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed to confirm concentration, purity, and reactivity. A comprehensive Certificate of Analysis (COA) detailing assay (by titration), solvent content, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and pyrophoric nature, it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Handle only in a certified fume hood or glovebox to prevent exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	Typically 1.6M to 2.5M in specified solvent (e.g., hexanes, cyclohexane)
Assay (Titration)	≥ 95%
Identity (IR / NMR)	Conforms to structure
Solvent	As specified (e.g., Hexanes, Cyclohexane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.