Description

Chloromethane Sulfonamide CAS NO 21335-43-3 is a versatile organosulfur compound featuring a sulfonamide functional group activated by a chloromethyl substituent. This molecular architecture makes it a valuable synthetic intermediate, particularly for the preparation of more complex sulfonamide derivatives and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. Its reactivity profile enables its use in nucleophilic substitution and coupling reactions, facilitating the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various sulfonamide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile reagent for constructing complex molecules in medicinal and organic chemistry.
• Dye and Pigment Manufacturing: Intermediate in the production of specialty dyes and colorants.
• Polymer Modification: Can be used to introduce sulfonamide functional groups into polymer chains to alter material properties.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal complexation.

Basic Information

Product Name	Chloromethane Sulfonamide
CAS No.	21335-43-3
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	N-(Chloromethyl)benzenesulfonamide; Benzenesulfonamide, N-(chloromethyl)-; Chloromethyl phenyl sulfonamide; N-Chloromethylbenzenesulfonamide; p-Toluenesulfonamide, N-(chloromethyl)- (common misassignment); Chloromethanesulfonanilide; BSA-Cl (in some contexts); (Chloromethyl)sulfonylbenzene amine
EINECS	Contact for details

Quality Control

Our Chloromethane Sulfonamide is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to potential sensitivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.