Description

Z-Pro-Val-Oh is a protected tripeptide derivative, widely utilized as a key building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex molecules. It is particularly valuable in the pharmaceutical and biotechnology sectors for peptide synthesis and medicinal chemistry research. Its consistent quality and reliable supply make it a critical component for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to construct specific peptide sequences with high fidelity.
• Medicinal Chemistry Research: Serves as a scaffold or precursor in structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Bioconjugation: Can be employed in the development of peptide-drug conjugates (PDCs) and other bioconjugate platforms.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides and organic compounds.

Basic Information

Product Name	Z-Pro-Val-Oh
CAS No.	21285-27-8
Molecular Formula	C19H24N2O5
Molecular Weight	360.41 g/mol
Synonyms	Z-Pro-Val-OH; Z-Pro-Val; CBZ-Pro-Val-OH; N-Carbobenzoxy-L-prolyl-L-valine; Nα-Carbobenzyloxy-L-prolyl-L-valine; (S)-2-(((S)-1-((Benzyloxy)carbonyl)pyrrolidine-2-carbonyl)amino)-3-methylbutanoic acid; Z-L-Pro-L-Val-OH; Benzyloxycarbonyl-L-prolyl-L-valine
EINECS	Contact for details

Quality Control

Our Z-Pro-Val-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.