Description

Z-Lys(Z)-Osu CAS NO 21160-83-8 is a protected amino acid derivative, specifically Nε-carbobenzyloxy-L-lysine N-hydroxysuccinimide ester, widely used as a key building block in peptide synthesis. This compound is valued for its role in introducing the lysine side chain with orthogonal protection, enabling the construction of complex peptides and bioconjugates. It is an essential reagent for researchers and manufacturers in pharmaceutical development, proteomics, and the production of therapeutic peptides and diagnostic reagents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the controlled incorporation of lysine residues with protected side chains.
• Bioconjugation and Labeling: Used to attach peptides, proteins, or other molecules to carriers, surfaces, or fluorescent probes via amine coupling.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Antibody-Drug Conjugate (ADC) Development: Facilitates the site-specific conjugation of cytotoxic payloads to antibodies.
• Research & Development: Employed in academic and industrial R&D for studying protein-protein interactions and developing novel biomaterials.
• Diagnostic Reagent Manufacturing: Used in the production of peptide antigens for immunoassays and diagnostic kits.

Basic Information

Product Name	Z-Lys(Z)-Osu
CAS No.	21160-83-8
Molecular Formula	C21H29N3O7
Molecular Weight	435.47 g/mol
Synonyms	Nε-Carbobenzyloxy-Nα-[(benzyloxy)carbonyl]-L-lysine N-hydroxysuccinimide Ester; Nα,Nε-Bis-Cbz-L-lysine N-hydroxysuccinimide Ester; Nα,Nε-Di-Z-L-lysine Succinimidyl Ester; (S)-2-((((Benzyloxy)carbonyl)amino)-6-((((benzyloxy)carbonyl)amino)hexanoic acid 2,5-dioxopyrrolidin-1-yl ester; Bis-Cbz-L-lysine-OSu; Z-Lys(Z)-OSU; Z-L-Lys(Z)-Osu; Nα,Nε-Bis-Cbz-L-lysine-OSU
EINECS	Contact for details

Quality Control

Our Z-Lys(Z)-Osu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.