Description

Z-Lys(Z)-Onp is a protected amino acid derivative widely used as a key building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily utilized in pharmaceutical R&D, biotechnology, and fine chemical production for developing therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected lysine derivative for the controlled incorporation of lysine residues.
• Solution-Phase Peptide Synthesis: Used as an activated ester intermediate for fragment condensation strategies.
• Pharmaceutical Intermediate: A critical raw material in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific labeling or modification of peptides and proteins.
• Research & Development: Employed in academic and industrial labs for novel peptide structure-activity relationship (SAR) studies.
• Production of Specialty Peptides: Used in manufacturing diagnostic peptides, antimicrobial peptides, and hormone analogs.

Basic Information

Product Name	Z-Lys(Z)-Onp
CAS No.	21160-82-7
Molecular Formula	C₂₇H₂₇N₃O₇
Molecular Weight	505.52 g/mol
Synonyms	N6,Nε-Bis(benzyloxycarbonyl)-L-lysine 4-nitrophenyl ester; Nα,Nε-Di-Z-L-lysine p-nitrophenyl ester; H-Lys(Z2)-ONp; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid 4-nitrophenyl ester (common Fmoc variant reference); Boc-Lys(Z)-ONp (common Boc variant reference); Z-Lys(Z)-OPhNO2; Lysine derivative, Z-protected ONp ester; Nα-Carbobenzoxy-Nε-carbobenzoxy-L-lysine p-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Z-Lys(Z)-Onp is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Melting Point	Specified range available on COA
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.