Description

Cobalt Mesoporphyrin is a synthetic metalloporphyrin complex where cobalt is coordinated within a mesoporphyrin IX ligand framework. This compound is valued for its role as a stable and effective heme oxygenase inhibitor, making it a critical research tool in biochemical and pharmacological studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for investigating cytoprotective mechanisms, oxidative stress, and inflammation pathways.

Application

• Biochemical Research: As a potent and selective inhibitor of heme oxygenase (HO) enzymes, particularly HO-1, for studying cellular stress response and cytoprotection.
• Pharmaceutical Development: Used in preclinical research to explore therapeutic interventions for conditions involving inflammation, ischemia-reperfusion injury, and organ transplantation.
• Cell Biology Studies: Employed in *in vitro* and *in vivo* models to modulate heme metabolism and investigate downstream signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Enzyme Inhibition Assays: A key reagent in enzymatic assays to quantify HO activity and screen for novel modulators.

Basic Information

Product Name	Cobalt Mesoporphyrin
CAS No.	21158-51-0
Molecular Formula	C₃₄H₃₆CoN₄O₄
Molecular Weight	623.61 g/mol
Synonyms	Cobalt(III) Mesoporphyrin IX; CoMP; CoMesoporphyrin; Cobalt Mesoporphyrin IX; Protoheme IX Cobalt Complex; Heme Oxygenase Inhibitor; Cobalt Protoporphyrin IX analog; CoPP-IX analog
EINECS	Contact for details

Quality Control

Our Cobalt Mesoporphyrin is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet the exacting standards of research and development, specifications can be aligned with specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Dark red to brown powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.