Description

Gpp-Li CAS NO 21141-43-5 is a specialized organolithium reagent, a powerful base and nucleophile widely utilized in advanced organic synthesis. Its high reactivity and selectivity make it an indispensable tool for constructing complex molecular architectures in research and industrial-scale processes. This compound is particularly valuable for pharmaceutical intermediates, agrochemicals, and materials science applications where precise carbon-carbon bond formation is critical.

Application

• Pharmaceutical Synthesis: Key reagent for the production of active pharmaceutical ingredients (APIs), especially in deprotonation and directed metalation reactions.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Materials Science: Employed as an initiator or catalyst in anionic polymerization for creating specialized polymers and advanced materials.
• Fine Chemical Production: Facilitates the synthesis of complex organic molecules, flavors, fragrances, and dyes.
• Lithiation Reactions: Effective for the regioselective lithiation of aromatic and heteroaromatic compounds.
• Academic & Industrial R&D: A fundamental reagent in method development and exploratory chemistry within research laboratories.

Basic Information

Product Name	Gpp-Li
CAS No.	21141-43-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lithium 2,2,6,6-Tetramethylpiperidide; Lithium TMP; LiTMP; 2,2,6,6-Tetramethylpiperidinolithium; TMP-Li; Lithium 2,2,6,6-tetramethylpiperidine-1-ide; Hindered lithium amide base
EINECS	Contact for details

Quality Control

Our Gpp-Li is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Due to its nature as a strong base and sensitivity to moisture and air, the material should be handled and stored under strictly anhydrous conditions. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder or solution
Identification (IR)	Conforms
Assay (Titration)	≥ 95.0%
Residual Solvent (GC)	To be specified per grade
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.