Description

2-Propanone, 1-Fluoro-1-Phenyl- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique structure, which combines a reactive carbonyl group with a fluorine atom and an aromatic ring, enabling precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the introduction of fluorine enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for novel fluorinated polymers and liquid crystals with tailored optical and electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic additions, and as a scaffold for constructing complex, fluorinated heterocycles.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of fluorine substitution on reactivity and molecular conformation.

Basic Information

Product Name	2-Propanone, 1-Fluoro-1-Phenyl-
CAS No.	21120-43-4
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	1-Fluoro-1-phenylacetone; α-Fluoroacetophenone; 1-Fluoro-1-phenylethanone; Phenylfluoromethyl methyl ketone; 2-Propanone, 1-fluoro-1-phenyl-; 1-Phenyl-1-fluoroacetone; Fluoromethyl phenyl ketone; (Fluorophenyl)acetone
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-Fluoro-1-Phenyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.