Description

Testosterone-2,2,4,6,6-D5 is a stable isotope-labeled analog of the primary male sex hormone, testosterone, where five hydrogen atoms are replaced by deuterium, making it an invaluable internal standard for analytical quantification. This high-purity reference material is critical for ensuring accuracy and reliability in mass spectrometry-based analyses, eliminating variability and providing definitive results. It is essential for research and quality control laboratories in the pharmaceutical, clinical diagnostics, and anti-doping sectors that require precise measurement of testosterone levels.

Application

• Internal Standard for LC-MS/MS & GC-MS: Primary use as a deuterated internal standard for the accurate quantification of endogenous testosterone in biological matrices (e.g., serum, plasma, urine).
• Pharmaceutical R&D & Bioanalysis: Used in pharmacokinetic and metabolism studies of testosterone-based therapeutics to track drug distribution and clearance.
• Clinical Diagnostics: Enables precise measurement of testosterone levels for diagnosing endocrine disorders such as hypogonadism.
• Anti-Doping Analysis: A crucial reference compound in sports drug testing laboratories to confirm the presence of exogenous testosterone and its metabolites.
• Metabolomics & Steroid Profiling: Facilitates targeted and untargeted analysis of steroid pathways in research on endocrinology and metabolic diseases.
• Method Development & Validation: Serves as a key component in developing, calibrating, and validating robust analytical methods for steroid hormone assays.

Basic Information

Product Name	Testosterone-2,2,4,6,6-D5
CAS No.	21002-80-2
Molecular Formula	C19H23D5O2
Molecular Weight	293.48 g/mol
Synonyms	Deuterated Testosterone (d5); [2,2,4,6,6-2H5]-Testosterone; 17β-Hydroxyandrost-4-en-3-one-2,2,4,6,6-d5; Androst-4-en-17β-ol-3-one-2,2,4,6,6-d5; Testosterone-d5; (8R,9S,10R,13S,14S,17S)-17-hydroxy-2,2,4,6,6-pentadeuterio-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
EINECS	Contact for details

Quality Control

Every batch of Testosterone-2,2,4,6,6-D5 is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity required for analytical reference standards. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.