Description

Gastrin Hexapeptide is a synthetic bioactive peptide fragment that mimics the C-terminal sequence of the natural gastrin hormone. This compound is a critical research tool for studying gastrointestinal physiology, hormone-receptor interactions, and gastric acid secretion mechanisms. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on metabolic and digestive system disorders.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating gastrin receptor (CCK2R) signaling pathways and gastric acid secretion.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the development of therapeutics for gastrointestinal diseases, including ulcers and gastrinomas.
• Biochemical Assays: Employed in in vitro and cell-based assays to evaluate receptor binding affinity, agonist/antagonist activity, and cellular response.
• Academic Studies: A fundamental tool in university and institutional labs for teaching and advanced research in endocrinology and peptide chemistry.
• Diagnostic Development: Potential use in the calibration and development of diagnostic kits for measuring gastrin-related biomarkers.

Basic Information

Product Name	Gastrin Hexapeptide
CAS No.	20994-88-1
Molecular Formula	C₃₇H₄₉N₇O₉S
Molecular Weight	767.9 g/mol
Synonyms	Gastrin I (1-6) hexapeptide; Pentagastrin C-terminal hexapeptide; Trp-Met-Asp-Phe-NH₂ (with protecting groups); H-Trp-Met-Asp-Phe-NH₂ derivative; CCK-8 (partial sequence); Cholecystokinin octapeptide fragment; Gastrin fragment 1-6; Research peptide 20994-88-1
EINECS	Contact for details

Quality Control

Every batch of our Gastrin Hexapeptide is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data including HPLC purity, MS confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.