Description

Cholecystokinin (27-33) is a bioactive heptapeptide fragment of the gastrointestinal hormone cholecystokinin. This specific sequence is crucial for research into neurological and digestive system functions, particularly in studying receptor binding and signal transduction pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, gastroenterology, and peptide-based drug discovery.

Application

• Neuroscientific Research: Used as a tool compound to study the role of CCK in anxiety, panic disorders, satiety, and pain modulation.
• Gastrointestinal Physiology Studies: Investigates CCK's effects on gallbladder contraction, pancreatic enzyme secretion, and gut motility.
• Receptor Binding Assays: Serves as a reference standard or ligand in competitive binding studies for CCKA and CCKB receptors.
• Pharmaceutical Development: Acts as a key intermediate or reference material in the development of CCK receptor agonists or antagonists.
• Biochemical Pathway Analysis: Employed in cell-based assays to elucidate intracellular signaling cascades activated by CCK receptor engagement.
• Academic & Clinical Research: Supports fundamental and translational research into brain-gut axis communication and related disorders.

Basic Information

Product Name	Cholecystokinin (27-33)
CAS No.	20988-64-1
Molecular Formula	C44H58N10O10S
Molecular Weight	919.06 g/mol
Synonyms	CCK (27-33); CCK-7; Cholecystokinin Fragment 27-33; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; CCK-8 (sulfated); Sincalide fragment; CCK Heptapeptide; Tyrosyl-O-sulfate-Met-Gly-Trp-Met-Asp-Phenylalaninamide
EINECS	Contact for details

Quality Control

Our Cholecystokinin (27-33) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.