Description

2-Chloro-6-Methylamino-Benzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and methylamino substituents, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated aniline core structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to introduce complex amine functionalities.
• Dye and Pigment Intermediate: Utilized in the production of specialized colorants and photographic chemicals.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new reaction pathways and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-6-Methylamino-Benzonitrile
CAS No.	20925-55-7
Molecular Formula	C8H7ClN2
Molecular Weight	166.61 g/mol
Synonyms	2-Chloro-6-(methylamino)benzonitrile; 6-Amino-2-chloro-N-methylbenzonitrile; Benzonitrile, 2-chloro-6-(methylamino)-; 2-Chloro-6-methylaminobenzonitrile; 2-Chloro-6-(N-methylamino)benzonitrile; 6-(Methylamino)-2-chlorobenzonitrile; 2-Chloro-6-(methylamino)benzonitrile; 20925-55-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylamino-Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, and NMR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.