Description

5-(Trifluoromethyl)-1,3-Benzoxazol-2-Amine is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is prized for its ability to impart unique physicochemical properties, such as enhanced metabolic stability and lipophilicity, to target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated motifs.
• Chemical Research & Development: An important reagent in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry Studies: Utilized in academic and industrial research to explore the effects of fluorine substitution on benzoxazole-based systems.

Basic Information

Product Name	5-(Trifluoromethyl)-1,3-Benzoxazol-2-Amine
CAS No.	20844-69-3
Molecular Formula	C8H5F3N2O
Molecular Weight	202.14 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)benzoxazole; 5-(Trifluoromethyl)-2-benzoxazolamine; 2-Benzoxazolamine, 5-(trifluoromethyl)-; 5-Trifluoromethyl-1,3-benzoxazol-2-ylamine; 5-Trifluoromethyl-2-aminobenzoxazole; 20844-69-3; 5-Trifluoromethylbenzoxazol-2-amine
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)-1,3-Benzoxazol-2-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.