Description

(2S)-2-{[(Benzyloxy)Carbonyl]Amino}-6-Formamidohexanoic Acid is a protected amino acid derivative, specifically an N-Cbz and N-formyl protected L-lysine analog, serving as a crucial chiral building block in organic synthesis. Its primary value lies in enabling the controlled, sequential assembly of complex peptides and peptidomimetics, where orthogonal protecting groups are essential. This high-purity intermediate is indispensable for researchers and manufacturers in pharmaceutical development, particularly for creating novel active pharmaceutical ingredients (APIs), and in advanced biochemical research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the solid-phase and solution-phase synthesis of peptide-based drugs and therapeutic candidates.
• Peptide Research: Used in academic and industrial laboratories for constructing complex peptide sequences with specific lysine modifications.
• Bioconjugation Chemistry: Serves as a precursor for introducing formyl-protected amino groups into biomolecules for linker attachment and labeling.
• Proteomics & Biochemistry: Employed in the study of enzyme-substrate interactions and the synthesis of enzyme inhibitors.
• Chemical Biology Tool Development: Utilized to create molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(2S)-2-{[(Benzyloxy)Carbonyl]Amino}-6-Formamidohexanoic Acid
CAS No.	20807-05-0
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	N6-Formyl-N2-[(benzyloxy)carbonyl]-L-lysine; Nα-Cbz-Nε-formyl-L-lysine; Fmoc-Lys(N-Formyl)-OH (precursor); Cbz-Lys(N-Formyl)-OH; (S)-2-((((Benzyloxy)carbonyl)amino)-6-formamidohexanoic acid; N-Formyl-Nα-Cbz-L-lysine; Nε-Formyl-Nα-carbobenzoxy-L-lysine; L-Lysine, N2-[(phenylmethoxy)carbonyl]-, N6-formyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity research chemicals. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific test results are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.