Description

9-[3-(Hydroxymethyl)-3-Deoxy-β-L-Threo-Tetrofuranosyl]-9H-Purin-6-Amine is a high-purity nucleoside derivative and a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the development of novel antiviral and anticancer therapeutics, where precise molecular structure is paramount for biological activity. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of nucleoside analogs and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies and metabolic pathway research.
• Antiviral Agent Development: Serves as a core structural component in the research and development of new therapeutic agents targeting viral polymerases.
• Nucleoside Chemistry: Employed in organic synthesis for the preparation of modified nucleosides and nucleotides with tailored properties.
• API Synthesis: Integrated into multi-step synthesis routes for the production of complex Active Pharmaceutical Ingredients (APIs).
• Life Science Reagents: Utilized in the formulation of high-purity biochemical reagents for diagnostic and research applications.

Basic Information

Product Name	9-[3-(Hydroxymethyl)-3-Deoxy-β-L-Threo-Tetrofuranosyl]-9H-Purin-6-Amine
CAS No.	20789-72-4
Molecular Formula	C₁₀H₁₃N₅O₄
Molecular Weight	267.24 g/mol
Synonyms	9-[(3-Hydroxymethyl-3-deoxy-β-L-threo-tetrofuranosyl)]adenine; 3'-Deoxy-3'-hydroxymethyladenine; 3'-C-Hydroxymethyladenosine; 3'-Deoxy-3'-(hydroxymethyl)adenosine; 9-(3-Deoxy-3-hydroxymethyl-β-L-threo-tetrofuranosyl)adenine; L-3'-Deoxy-3'-hydroxymethyladenosine; Adenine L-nucleoside derivative
EINECS	Contact for details

Quality Control

Our 9-[3-(Hydroxymethyl)-3-Deoxy-β-L-Threo-Tetrofuranosyl]-9H-Purin-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.