Description

2-Chloro-1-Pyrrolidin-1-Yl-Ethanone is a versatile and highly reactive organic building block, primarily used as an acylating agent in advanced chemical synthesis. Its core value lies in its ability to efficiently introduce the 2-chloroacetyl moiety into pyrrolidine-containing structures, facilitating the creation of complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its reactive chloroacetyl group is instrumental in building active molecular frameworks.
• Chemical Research & Development: Serves as a fundamental reagent in organic chemistry labs for constructing heterocyclic compounds and studying new reaction pathways.
• Peptidomimetic & Protease Inhibitor Development: Employed in the design and synthesis of peptide analogs and enzyme inhibitors due to its electrophilic character.
• Material Science Precursor: Acts as a starting material for synthesizing specialized polymers or functionalized surfaces with specific chemical properties.

Basic Information

Product Name	2-Chloro-1-Pyrrolidin-1-Yl-Ethanone
CAS No.	20266-00-6
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	2-Chloro-1-(pyrrolidin-1-yl)ethanone; 1-(2-Chloroacetyl)pyrrolidine; 2-Chloro-1-(1-pyrrolidinyl)ethanone; N-(2-Chloroacetyl)pyrrolidine; Chloroacetylpyrrolidine; Pyrrolidine, 1-(2-chloroacetyl)-; α-Chloro-1-pyrrolidinoethanone
EINECS	243-681-6

Quality Control

Our 2-Chloro-1-Pyrrolidin-1-Yl-Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its reactivity, it should be handled and stored with appropriate precautions to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.