Description

3-Hydroxycyclobutanecarbonitrile is a versatile and high-value organic nitrile building block, essential for advanced synthetic chemistry. Its unique structure, featuring both a hydroxyl group and a nitrile on a strained cyclobutane ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its strained ring system for unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and mechanical properties.
• Chemical Research: A valuable building block in academic and industrial R&D for exploring new reaction pathways and synthesizing complex natural product analogs.
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	3-Hydroxycyclobutanecarbonitrile
CAS No.	20249-17-6
Molecular Formula	C5H7NO
Molecular Weight	97.12 g/mol
Synonyms	3-Hydroxycyclobutanecarbonitrile; 3-Hydroxycyclobutanenitrile; 3-Cyano-1-cyclobutanol; 1-Cyclobutanol-3-carbonitrile; 3-Hydroxy-1-cyclobutanecarbonitrile; Cyclobutanol-3-carbonitrile; 3-Hydroxycyclobutyl cyanide; (3-Hydroxycyclobutyl)methanenitrile
EINECS	Contact for details

Quality Control

Our 3-Hydroxycyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.