Description

SKF-38393 (Hydrobromide) is a selective dopamine D1 receptor partial agonist, a high-purity research chemical of significant pharmacological interest. Its primary value lies in enabling critical neuroscience and neuropharmacology research, particularly in the study of dopamine receptor function, behavior, and potential therapeutic pathways. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on central nervous system disorders, addiction research, and psychiatric conditions.

Application

• Neuroscience Research: A key tool for studying dopamine D1 receptor signaling, localization, and downstream effects in neuronal models.
• Pharmacological Profiling: Used in in vitro and in vivo assays to characterize receptor-ligand interactions and efficacy.
• Behavioral Studies: Employed in preclinical research to investigate the role of D1 receptors in cognition, motivation, locomotion, and reward.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel therapeutics for Parkinson's disease, schizophrenia, and addiction.
• Biochemical Assays: Used in receptor binding studies, functional cAMP assays, and other molecular pharmacology experiments.
• Academic & Institutional Research: Fundamental reagent for university and government labs advancing the understanding of dopaminergic systems.

Basic Information

Item	Detail
Product Name	SKF-38393 (Hydrobromide)
CAS No.	20012-10-6
Molecular Formula	C16H18BrNO2 • HBr
Molecular Weight	409.14 g/mol
Synonyms	SKF-38393 HBr; (±)-SKF-38393 hydrobromide; 1-Phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide; 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide; SKF 38393; SKF38393; Benzazepine, 7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-, hydrobromide
EINECS	Contact for details

Quality Control

Every batch of SKF-38393 (Hydrobromide) is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency suitable for advanced research applications. We provide comprehensive analytical documentation, including HPLC chromatograms and full spectral data (NMR, MS). A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.