Description

3-Chloro-4-Fluorobenzyl Chloride is a versatile and reactive bifunctional aromatic intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive benzyl chloride group and halogenated aromatic ring, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzyl moiety.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the chloro and fluoro substituents enhance biological activity.
• Liquid Crystal Materials: Serves as a building block for the production of fluorinated liquid crystals used in display technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and resins.
• Organic Synthesis Reagent: Employed in research laboratories for nucleophilic substitution reactions and to introduce the 3-chloro-4-fluorobenzyl group into target molecules.
• Dye and Pigment Industry: Intermediate in the production of complex dyes and organic pigments.

Basic Information

Product Name	3-Chloro-4-Fluorobenzyl Chloride
CAS No.	2994-69-6
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	1-(Chloromethyl)-3-chloro-4-fluorobenzene; α,3-Dichloro-4-fluorotoluene; 3-Chloro-4-fluorobenzylchloride; 4-Fluoro-3-chlorobenzyl Chloride; (3-Chloro-4-fluorophenyl)methyl chloride; Benzene, 1-(chloromethyl)-3-chloro-4-fluoro-; 3-Chloro-4-fluoro-α-chlorotoluene
EINECS	221-069-1

Quality Control

Our 3-Chloro-4-Fluorobenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.