Description

Nonafluoro-1-Butanesulfonyl Chloride is a high-value perfluorinated sulfonyl chloride derivative, serving as a critical building block for introducing the highly stable and lipophilic perfluorobutylsulfonyl group. This compound matters for its ability to impart unique properties such as enhanced chemical stability, hydrophobicity, and electronic characteristics to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing specialty chemicals, catalysts, and functional polymers.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to create novel herbicides and pesticides with improved environmental persistence and efficacy.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to produce fluorinated polymers with superior chemical resistance and low surface energy.
• Catalyst & Ligand Preparation: Essential for creating specialized perfluorinated sulfonamide ligands used in catalysis and metal-organic frameworks (MOFs).
• Surface Treatment Agents: Employed in the synthesis of coatings and surface modifiers to achieve oil-, water-, and stain-repellent properties.
• Electrolyte Additives: Investigated for use in lithium-ion battery electrolytes to enhance stability and performance at high voltages.
• Organic Synthesis Reagent: A versatile reagent for introducing the nonafluorobutanesulfonyl (Nf) protecting group or as a sulfonylation agent in complex organic transformations.

Basic Information

Product Name	Nonafluoro-1-Butanesulfonyl Chloride
CAS No.	2991-84-6
Molecular Formula	C₄F₉SO₂Cl
Molecular Weight	332.54 g/mol
Synonyms	1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-sulfonyl Chloride; Perfluorobutanesulfonyl Chloride; Nonafluorobutanesulfonyl Chloride; Nf Chloride; Nonafluoro-1-butanesulfonic Acid Chloride; C4F9SO2Cl; PFBS Chloride; Nonaflyl Chloride
EINECS	221-061-1

Quality Control

Our Nonafluoro-1-Butanesulfonyl Chloride is produced and tested under stringent quality management systems. Each batch is analyzed to ensure high chemical purity and consistency, with typical purity levels exceeding 97% (GC). We provide comprehensive Certificates of Analysis (COA) upon request, detailing assay, identity confirmation, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases and nucleophiles. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.