Description

3,3,3-Trifluoropropylamine Hydrochloride is a high-purity fluorinated amine salt, a key building block for introducing the trifluoropropyl group into complex molecular architectures. This compound is valued for its role in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug discovery.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the trifluoropropyl moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving their dielectric and optical properties.
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Acts as a versatile reagent in nucleophilic substitution and reductive amination reactions to incorporate fluorinated alkyl chains.
• Fluorinated Surfactant Precursor: Used in the development of specialty surfactants and coatings with unique wetting and leveling characteristics.

Basic Information

Product Name	3,3,3-Trifluoropropylamine Hydrochloride
CAS No.	2968-33-4
Molecular Formula	C3H7F3N · HCl
Molecular Weight	153.55 g/mol
Synonyms	3,3,3-Trifluoropropan-1-amine hydrochloride; 3-(Trifluoromethyl)propylamine hydrochloride; 1-Amino-3,3,3-trifluoropropane hydrochloride; 3,3,3-Trifluoro-1-propanamine hydrochloride; γ-Trifluoropropylamine hydrochloride; 3,3,3-Trifluoropropylammonium chloride
EINECS	221-001-7

Quality Control

Our 3,3,3-Trifluoropropylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and KF titration, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.