Description

2,3,3,3-Tetrafluoro-2-(trifluoromethoxy)propionyl fluoride is a highly fluorinated acid fluoride derivative, serving as a critical building block in advanced chemical synthesis. This compound matters for its unique reactivity profile, enabling the efficient introduction of perfluoroalkoxy functionalities into target molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key synthon for introducing fluorinated motifs into drug candidates to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where fluorine atoms improve efficacy and environmental persistence.
• Fluoropolymer Modification: Serves as a monomer or grafting agent for synthesizing and modifying specialty fluoropolymers with unique surface properties and chemical resistance.
• Liquid Crystal & Electronic Materials: A precursor for fluorine-containing compounds used in liquid crystal displays (LCDs) and dielectric materials for the electronics industry.
• Organic Synthesis Reagent: Employed in academic and industrial research laboratories for constructing complex fluorinated organic molecules.
• Surface Treatment Agent: Imparts oil-, water-, and stain-repellent characteristics to textiles, papers, and other substrates.

Basic Information

Product Name	2,3,3,3-Tetrafluoro-2-(trifluoromethoxy)propionyl Fluoride
CAS No.	2927-83-5
Molecular Formula	C4F8O2
Molecular Weight	232.03 g/mol
Synonyms	Perfluoro(methyl vinyl ether) carbonyl fluoride; 2-(Trifluoromethoxy)-3,3,3-trifluoropropionyl fluoride; 3,3,3-Trifluoro-2-(trifluoromethoxy)propanoic acid fluoride; 2,3,3,3-Tetrafluoro-2-(trifluoromethoxy)propanoyl fluoride; Pentafluoro(trifluoromethoxy)acetyl fluoride; Hexafluoromethoxyacetyl fluoride (related); TFMPF (abbreviation); Perfluoromethoxypropionyl fluoride
EINECS	220-896-7

Quality Control

Our 2,3,3,3-Tetrafluoro-2-(trifluoromethoxy)propionyl fluoride is manufactured under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability, given its moisture-sensitive (hygroscopic) nature. Keep away from strong bases, oxidizing agents, and sources of ignition. Containers must be kept tightly sealed under a dry, inert atmosphere (e.g., nitrogen) to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Acidity (Titration)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.