Description

2-Cyclobuten-1-One, 2-Chloro-4,4-Difluoro-3-Hydroxy- is a highly functionalized cyclobutenone derivative, serving as a versatile and advanced synthetic intermediate in modern organic chemistry. Its unique structure, featuring a reactive ketone, halogen, fluorine, and hydroxyl groups, makes it a critical building block for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the stability and bioactivity imparted by the difluoro and chloro substituents.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry: A valuable substrate for studying novel fluorination reactions and creating libraries of fluorinated organic molecules for screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals and target molecules.

Basic Information

Product Name	2-Cyclobuten-1-One, 2-Chloro-4,4-Difluoro-3-Hydroxy-
CAS No.	2927-62-0
Molecular Formula	C4H3ClF2O2
Molecular Weight	156.52 g/mol
Synonyms	2-Chloro-4,4-difluoro-3-hydroxy-2-cyclobuten-1-one; 3-Hydroxy-2-chloro-4,4-difluorocyclobut-2-en-1-one; 2-Chloro-4,4-difluoro-3-hydroxycyclobut-2-enone; 4,4-Difluoro-2-chloro-3-hydroxy-2-cyclobuten-1-one; 2927-62-0; 2-Cyclobuten-1-one, 2-chloro-4,4-difluoro-3-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Cyclobuten-1-One, 2-Chloro-4,4-Difluoro-3-Hydroxy- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.