Description

2,2-Bis(Trifluoromethyl)Propanol is a specialized fluorinated alcohol characterized by its unique geminal bis(trifluoromethyl) group. This structure imparts exceptional properties, including high volatility and significant chemical stability, making it a valuable intermediate for advanced synthesis. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms improves efficacy and environmental persistence.
• Specialty Polymer & Material Science: Acts as a monomer or modifier for creating high-performance fluoropolymers with superior chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated liquid crystals and dielectric fluids for display technologies and advanced electronics.
• Catalyst & Ligand Preparation: Utilized to prepare novel fluorinated ligands for catalysis, enabling unique reaction pathways and selectivities in fine chemical synthesis.
• Surface Modification Agent: Applied to alter surface properties of materials, providing oil, water, and stain repellency.

Basic Information

Product Name	2,2-Bis(Trifluoromethyl)Propanol
CAS No.	2927-17-5
Molecular Formula	C5H6F6O
Molecular Weight	196.09 g/mol
Synonyms	1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)propan-2-ol; Hexafluoro-2-(trifluoromethyl)-2-propanol; 2-Propanol, 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-1,1,1,3,3,3-hexafluoro-2-propanol; HFIP-Diol (common abbreviation); Perfluoro-tert-butanol (historical); PFTB; Nonaffluoro-tert-butyl alcohol
EINECS	220-882-8

Quality Control

Every batch of 2,2-Bis(Trifluoromethyl)Propanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.300 - 1.310
Density (20°C)	1.65 - 1.70 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.