Description

1-(1-Chloro-2,2,2-Trifluoro-Ethyl)-3-(Trifluoromethyl)Benzene is a high-value fluorinated aromatic building block characterized by its unique trifluoromethyl and chlorotrifluoroethyl substituents. This compound matters for its role in introducing lipophilicity and metabolic stability into advanced chemical structures, which is critical for developing high-performance materials and active ingredients. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials industries seeking to innovate with fluorine chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and CNS drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the synthesis of electronic materials for displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex fluorinated molecules.
• Research & Development: Essential for academic and industrial labs exploring new reactions and properties of polyfluorinated aromatic systems.

Basic Information

Product Name	1-(1-Chloro-2,2,2-Trifluoro-Ethyl)-3-(Trifluoromethyl)Benzene
CAS No.	2925-57-7
Molecular Formula	C9H5ClF6
Molecular Weight	262.58 g/mol
Synonyms	3-(Trifluoromethyl)-α-(trifluoromethyl)benzyl chloride; 1-Chloro-2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]ethane; α-Chloro-α,α,α,3-tetrafluorotoluene; 1-(3-Trifluoromethylphenyl)-2,2,2-trifluoroethyl chloride; 3-Trifluoromethylbenzotrifluoride, chlorinated derivative; (3-Trifluoromethylphenyl)chlorodifluoromethane (common name variant); Benzene, 1-(1-chloro-2,2,2-trifluoroethyl)-3-(trifluoromethyl)-
EINECS	220-882-8

Quality Control

Our 1-(1-Chloro-2,2,2-Trifluoro-Ethyl)-3-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.5 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.